Dear Fran - 

 Good question.  Fortunately, the answer is no (or let's just say 99.9% no) is doesn't cause keloids.  There are several reasons for this.  First, we get less prone to keloids as we get older (keloids peak in the teens and 20s).  Second, the face of a woman is less likely to keloid than say, the arm, the ear, or the abdomen.  And third, the needles we use for Botox are so tiny (like an accupuncture needle), that they often don't even leave a mark even for the day.  I think it would be safe for you to give it a try.  Just tell your doctor or nurse about your keloid history.  Good luck!!  Dr. I