Since the purpose of Thermage is to tighten a little, maintain the jawline and eyebrow position, and build collagen, the timing of Botox with it really isn't important.   But, if you're doing a laser treatment or series of them with the purpose of reducing wrinkles, then you want to do your Botox 1-2 weeks before the laser so that the face is more relaxed (wrinkling less from facial movement) while you are healing.   Dr. I