Could Coolsculpting work for other causes of large thighs or puffiness?
Coolsculpting is really designed to kill fat cells and nothing else. So unfortunately, the answer is no. Also, since it relies on the lymph system and the blood supply in the area treated to carry away and get rid of the dead fat cells, it could potentially make the lymphedema much worse and delay healing from the Coolsculpting. More on Coolsculpting.
Options to consider with the approval of your doctor might be regular therapeutic massage, acupuncture or other manual therapies that help mobilize fluid in an area.
Hope this helps, Dr. I